Progressive lysosomal membrane permeabilization induced by iron oxide nanoparticles drives hepatic cell autophagy and apoptosis

Progressive lysosomal membrane permeabilization induced by iron oxide nanoparticles drives hepatic cell autophagy and apoptosis

Abstract Iron oxide nanoparticles (IONs) are frequently used in various biomedical applications, in particular as magnetic resonance imaging contrast agents in liver imaging. Indeed, number of IONs have been withdrawn due to their poor clinical performance. Yet comprehensive understanding of their i...

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Bibliographic Details
Main Authors: Kateryna Levada, Stanislav Pshenichnikov, Alexander Omelyanchik, Valeria Rodionova, Aleksey Nikitin, Alexander Savchenko, Igor Schetinin, Dmitry Zhukov, Maxim Abakumov, Alexander Majouga, Mariia Lunova, Milan Jirsa, Barbora Smolková, Mariia Uzhytchak, Alexandr Dejneka, Oleg Lunov
Format: Article
Language:English
Published: SpringerOpen 2020-05-01
Series:Nano Convergence
Subjects:
Cytotoxicity
Apoptosis
Autophagy
Iron oxide nanoparticles
Magnetic resonance imaging
Online Access:http://link.springer.com/article/10.1186/s40580-020-00228-5

Internet

http://link.springer.com/article/10.1186/s40580-020-00228-5

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