The role of cGMP on adenosine A1 receptor-mediated inhibition of synaptic transmission at the hippocampus

Both adenosine A1 receptor and cGMP inhibit synaptic transmission at the hippocampus and recently it was found that A1 receptor increased cGMP levels in hippocampus, but the role of cGMP on A1 receptor-mediated inhibition of synaptic transmission remains to be established. In the present work we inv...

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Bibliographic Details
Main Authors: Isa ePinto, André eSerpa, Ana Maria Sebastião, José Francisco Cascalheira
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00103/full