The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction

The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction

The discovery of environmentally specific genetic effects is crucial to the understanding of complex traits, such as susceptibility to noise-induced hearing loss (NIHL). We describe the first genome-wide association study (GWAS) for NIHL in a large and well-characterized population of inbred mouse s...

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Bibliographic Details
Main Authors: Joel Lavinsky, Marshall Ge, Amanda L. Crow, Calvin Pan, Juemei Wang, Pezhman Salehi, Anthony Myint, Eleazar Eskin, Hooman Allayee, Aldons J. Lusis, Rick A. Friedman
Format: Article
Language:English
Published: Oxford University Press 2016-10-01
Series:G3: Genes, Genomes, Genetics
Subjects:
GWAS
NIHL
gene-by-environment
HMDP
eQTL
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.032516

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.032516

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