Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

<p>Abstract</p> <p>Background</p> <p>Haplotype based linkage disequilibrium (LD) mapping has become a powerful and cost-effective method for performing genetic association studies, particularly in the search for genetic markers in linkage disequilibrium with complex dis...

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Bibliographic Details
Main Authors: Morabia Alfredo, Sheng Huitao, Zhang Peisen, Gilliam T Conrad
Format: Article
Language:English
Published: BMC 2003-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2105/4/3

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