Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping
<p>Abstract</p> <p>Background</p> <p>Haplotype based linkage disequilibrium (LD) mapping has become a powerful and cost-effective method for performing genetic association studies, particularly in the search for genetic markers in linkage disequilibrium with complex dis...
Main Authors: | Morabia Alfredo, Sheng Huitao, Zhang Peisen, Gilliam T Conrad |
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Format: | Article |
Language: | English |
Published: |
BMC
2003-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2105/4/3 |
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