Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

<p>Abstract</p> <p>Background</p> <p>Haplotype based linkage disequilibrium (LD) mapping has become a powerful and cost-effective method for performing genetic association studies, particularly in the search for genetic markers in linkage disequilibrium with complex dis...

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Bibliographic Details
Main Authors: Morabia Alfredo, Sheng Huitao, Zhang Peisen, Gilliam T Conrad
Format: Article
Language:English
Published: BMC 2003-01-01
Series:BMC Bioinformatics
Subjects:
Haplotype frequency estimation
Expectation Maximization Algorithm
Genotype
Lipoprotein Lipase
Online Access:http://www.biomedcentral.com/1471-2105/4/3

Internet

http://www.biomedcentral.com/1471-2105/4/3

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