Robust computational analysis of rRNA hypervariable tag datasets.

Next-generation DNA sequencing is increasingly being utilized to probe microbial communities, such as gastrointestinal microbiomes, where it is important to be able to quantify measures of abundance and diversity. The fragmented nature of the 16S rRNA datasets obtained, coupled with their unpreceden...

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Bibliographic Details
Main Authors: Maksim Sipos, Patricio Jeraldo, Nicholas Chia, Ani Qu, A Singh Dhillon, Michael E Konkel, Karen E Nelson, Bryan A White, Nigel Goldenfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3013109?pdf=render