SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells

SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells

Abstract Background Abdominal aortic aneurysm (AAA) is a deadly cardiovascular disease characterised by the gradual, irreversible dilation of the abdominal aorta. AAA is a complex genetic disease but little is known about the role of epigenetics. Our objective was to determine if global DNA methylat...

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Bibliographic Details
Main Authors: Bradley J. Toghill, Athanasios Saratzis, Peter J. Freeman, Nicolas Sylvius, UKAGS collaborators, Matthew J. Bown
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Clinical Epigenetics
Subjects:
Epigenetics
Vascular disease
Aneurysm
Inflammation
Online Access:http://link.springer.com/article/10.1186/s13148-018-0460-9

Internet

http://link.springer.com/article/10.1186/s13148-018-0460-9

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