Overexpression of claspin promotes docetaxel resistance and is associated with prostate‐specific antigen recurrence in prostate cancer

Overexpression of claspin promotes docetaxel resistance and is associated with prostate‐specific antigen recurrence in prostate cancer

Abstract Although docetaxel (DTX) confers significant survival benefits in patients with castration‐resistant prostate cancer (CRPC), resistance to DTX inevitably occurs. Therefore, clarifying the mechanisms of DTX resistance may improve survival in patients with CRPC. Claspin plays a pivotal role i...

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Bibliographic Details
Main Authors: Takashi Babasaki, Kazuhiro Sentani, Yohei Sekino, Go Kobayashi, Quoc Thang Pham, Narutaka Katsuya, Shintaro Akabane, Daiki Taniyama, Tetsutaro Hayashi, Masaki Shiota, Naohide Oue, Jun Teishima, Akio Matsubara, Wataru Yasui
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Cancer Medicine
Subjects:
cell cycle checkpoint
claspin
DNA damage repair
docetaxel resistance
prostate cancer
Online Access:https://doi.org/10.1002/cam4.4113

Internet

https://doi.org/10.1002/cam4.4113

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