Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8+ and CD4+ T Cells

Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8+ and CD4+ T Cells

Dendritic cells (DCs) are major antigen-presenting cells that can efficiently prime and cross-prime antigen-specific T cells. Delivering antigen to DCs via surface receptors is thus an appealing strategy to evoke cellular immunity. Nonetheless, which DC surface receptor to target to yield the optima...

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Bibliographic Details
Main Authors: Wenjie Yin, Laurent Gorvel, Sandra Zurawski, Dapeng Li, Ling Ni, Dorothée Duluc, Katherine Upchurch, JongRok Kim, Chao Gu, Richard Ouedraogo, Zhiqing Wang, Yaming Xue, HyeMee Joo, Jean-Pierre Gorvel, Gerard Zurawski, SangKon Oh
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:EBioMedicine
Subjects:
Dendritic cell
Cross-presentation
CD40
Lectins
Vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416300263

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http://www.sciencedirect.com/science/article/pii/S2352396416300263

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