Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria

Abstract Background Most amino acids are encoded by multiple synonymous codons. However, synonymous codons are not used equally, and this biased codon use varies between different organisms. It has previously been shown that both selection acting to increase codon translational efficiency and select...

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Bibliographic Details
Main Authors: Emily A. Seward, Steven Kelly
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-018-1480-7