Design, Synthesis and Anticancer Evaluation of Novel Quinazoline-Sulfonamide Hybrids

By combining the structural features of quinazoline and sulfonamides, novel hybrid compounds 2–21 were synthesized using a simple and convenient method. Evaluation of these compounds against different cell lines identified compounds 7 and 17 as most active anticancer agents as they showed effectiven...

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Bibliographic Details
Main Authors: Mostafa M. Ghorab, Mansour S. Alsaid, Mohammed S. Al-Dosari, Marwa G. El-Gazzar, Mohammad K. Parvez
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/2/189