Immature Immunoglobulin Gene Rearrangements Are Recurrent in B Precursor Adult Acute Lymphoblastic Leukemia Carrying <i>TP53</i> Molecular Alterations

Immature Immunoglobulin Gene Rearrangements Are Recurrent in B Precursor Adult Acute Lymphoblastic Leukemia Carrying <i>TP53</i> Molecular Alterations

Here, we describe the immunoglobulin and T cell receptor (Ig/TCR) molecular rearrangements identified as a leukemic clone hallmark for minimal residual disease assessment in relation to <i>TP53</i> mutational status in 171 Ph-negative Acute Lymphoblastic Leukemia (ALL) adult patients at...

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Bibliographic Details
Main Authors: Silvia Salmoiraghi, Roberta Cavagna, Marie Lorena Guinea Montalvo, Greta Ubiali, Manuela Tosi, Barbara Peruta, Tamara Intermesoli, Elena Oldani, Anna Salvi, Chiara Pavoni, Ursula Giussani, Renato Bassan, Alessandro Rambaldi, Orietta Spinelli
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Genes
Subjects:
acute lymphoblastic leukemia
<i>TP53</i>
immunoglobulin rearrangements
Online Access:https://www.mdpi.com/2073-4425/11/9/960

Internet

https://www.mdpi.com/2073-4425/11/9/960

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