Anticonvulsant Effects by Bilateral and Unilateral Transplantation of GABA-Producing Cells into the Subthalamic Nucleus in an Acute Seizure Model

Neural transplantation of GABA-producing cells into key structures within seizure-suppressing circuits holds promise for medication-resistant epilepsy patients not eligible for resection of the epileptic focus. The substantia nigra pars reticulata (SNr), a basal ganglia output structure, is well kno...

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Bibliographic Details
Main Authors: Annelie Handreck, Bianca Backofen-Wehrhahn, Sonja Bröer, Wolfgang Löscher, Manuela Gernert
Format: Article
Language:English
Published: SAGE Publishing 2014-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X658944