Essential Oil, Extracts, and Sesquiterpenes Obtained From the Heartwood of Pilgerodendron uviferum Act as Potential Inhibitors of the Staphylococcus aureus NorA Multidrug Efflux Pump

Essential Oil, Extracts, and Sesquiterpenes Obtained From the Heartwood of Pilgerodendron uviferum Act as Potential Inhibitors of the Staphylococcus aureus NorA Multidrug Efflux Pump

Staphylococcus aureus is a serious human pathogen that is highly adaptive to environmental conditions and rapidly develops antibiotic resistance. The use of efflux pumps to reduce antibiotic concentrations at the intracellular level is one of the main mechanisms by which bacteria develop antibiotic...

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Bibliographic Details
Main Authors: Javier Espinoza, Alejandro Urzúa, Loreto Sanhueza, Mariana Walter, Paola Fincheira, Patricia Muñoz, Leonora Mendoza, Marcela Wilkens
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
antibiotic resistance
efflux pump
NorA
efflux pumps inhibitors
sesquiterpenes
15-copaenol
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00337/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00337/full

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