A Pilot Study Investigating Changes in Capillary Hemodynamics and Its Modulation by Exercise in the APP-PS1 Alzheimer Mouse Model

Dysfunction in neurovascular coupling that results in a mismatch between cerebral blood flow and neuronal activity has been suggested to play a key role in the pathogenesis of Alzheimer’s disease (AD). Meanwhile, physical exercise is a powerful approach for maintaining cognitive health and could pla...

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Bibliographic Details
Main Authors: Xuecong Lu, Mohammad Moeini, Baoqiang Li, Yuankang Lu, Rafat Damseh, Philippe Pouliot, Éric Thorin, Frédéric Lesage
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01261/full