Strategies and Challenges to Improve Cellular Programming-Based Approaches for Heart Regeneration Therapy

Strategies and Challenges to Improve Cellular Programming-Based Approaches for Heart Regeneration Therapy

Limited adult cardiac cell proliferation after cardiovascular disease, such as heart failure, hampers regeneration, resulting in a major loss of cardiomyocytes (CMs) at the site of injury. Recent studies in cellular reprogramming approaches have provided the opportunity to improve upon previous tech...

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Bibliographic Details
Main Authors: Lin Jiang, Jialiang Liang, Wei Huang, Zhichao Wu, Christian Paul, Yigang Wang
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Heart regeneration
induced pluripotent stem cells
cardiac differentiation
direct reprogramming
cardiomyocyte
fibroblasts
Online Access:https://www.mdpi.com/1422-0067/21/20/7662

Internet

https://www.mdpi.com/1422-0067/21/20/7662

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