The multidrug resistance 1 gene Abcb1 in brain and placenta: comparative analysis in human and guinea pig.

The multidrug resistance 1 gene Abcb1 in brain and placenta: comparative analysis in human and guinea pig.

The Multidrug Resistance 1 (MDR1; alternatively ABCB1) gene product P-glycoprotein (P-gp), an ATP binding cassette transporter, extrudes multiple endogenous and exogenous substrates from the cell, playing an important role in normal physiology and xenobiotic distribution and bioavailability. To date...

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Bibliographic Details
Main Authors: Jane J Pappas, Sophie Petropoulos, Matthew Suderman, Majid Iqbal, Vasilis Moisiadis, Gustavo Turecki, Stephen G Matthews, Moshe Szyf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4213008?pdf=render

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http://europepmc.org/articles/PMC4213008?pdf=render

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