Non-inferiority trial comparing cigarette consumption, adoption rates, acceptability, tolerability, and tobacco harm reduction potential in smokers switching to Heated Tobacco Products or electronic cigarettes: Study protocol for a randomized controlled trial

Background: Despite the introduction of tobacco control measures, smoking remains highly prevalent in most EU countries. In Italy, one in four adults were still regular smokers in 2017. Increasing use of combustion-free delivering nicotine technologies for cigarette substitution may accelerate the c...

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Main Authors: Pasquale Caponnetto, Massimo Caruso, Marilena Maglia, Rosalia Emma, Daniela Saitta, Barbara Busà, Riccardo Polosa, Umberto Prosperini, Alfio Pennisi, Francesca Benfatto, Carlo Sartorio, Matteo Guastella, Enrico Mondati
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865420300028