Multicolor imaging of calcium-binding proteins in human kidney stones for elucidating the effects of proteins on crystal growth

Abstract The pathogenesis of kidney stone formation includes multi-step processes involving complex interactions between mineral components and protein matrix. Calcium-binding proteins in kidney stones have great influences on the stone formation. The spatial distributions of these proteins in kidne...

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Bibliographic Details
Main Authors: Yutaro Tanaka, Mihoko Maruyama, Atsushi Okada, Yoshihiro Furukawa, Koichi Momma, Yuki Sugiura, Rie Tajiri, Koichi P. Sawada, Shunichi Tanaka, Kazufumi Takano, Kazumi Taguchi, Shuzo Hamamoto, Ryosuke Ando, Katsuo Tsukamoto, Masashi Yoshimura, Yusuke Mori, Takahiro Yasui
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95782-1