Interactions of 172 plant extracts with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8): a study on herb-drug interactions

Background Herb-drug interactions (HDIs) resulting from concomitant use of herbal products with clinical drugs may cause adverse reactions. Organic anion transporter 1 (OAT1) and 3 (OAT3) are highly expressed in the kidney and play a key role in the renal elimination of substrate drugs. So far, litt...

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Bibliographic Details
Main Authors: Hang Lu, Zhiqiang Lu, Xue Li, Gentao Li, Yilin Qiao, Robert P. Borris, Youcai Zhang
Format: Article
Language:English
Published: PeerJ Inc. 2017-05-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3333.pdf