The glutaredoxin mono- and di-thiol mechanisms for deglutathionylation are functionally equivalent: implications for redox systems biology

Glutathionylation plays a central role in cellular redox regulation and anti-oxidative defence. Grx (Glutaredoxins) are primarily responsible for reversing glutathionylation and their activity therefore affects a range of cellular processes, making them prime candidates for computational systems bi...

Full description

Bibliographic Details
Main Authors: Lefentse N. Mashamaite, Johann M. Rohwer, Ché S. Pillay
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2015-02-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/035/e173/bsr035e173.htm