A Novel Methodology to Estimate Metabolic Flux Distributions in Constraint-Based Models

Quite generally, constraint-based metabolic flux analysis describes the space of viable flux configurations for a metabolic network as a high-dimensional polytope defined by the linear constraints that enforce the balancing of production and consumption fluxes for each chemical species in the system...

Full description

Bibliographic Details
Main Authors: Francesco Alessandro Massucci, Isaac Pérez Castillo, Andrea De Martino, Francesc Font-Clos
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/3/3/838