Reconstructing DNA copy number by joint segmentation of multiple sequences

<p>Abstract</p> <p>Background</p> <p>Variations in DNA copy number carry information on the modalities of genome evolution and mis-regulation of DNA replication in cancer cells. Their study can help localize tumor suppressor genes, distinguish different populations of c...

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Bibliographic Details
Main Authors: Zhang Zhongyang, Lange Kenneth, Sabatti Chiara
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2105/13/205