Critical and Supercritical Spatiotemporal Calcium Dynamics in Beta Cells

Critical and Supercritical Spatiotemporal Calcium Dynamics in Beta Cells

A coordinated functioning of beta cells within pancreatic islets is mediated by oscillatory membrane depolarization and subsequent changes in cytoplasmic calcium concentration. While gap junctions allow for intraislet information exchange, beta cells within islets form complex syncytia that are intr...

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Bibliographic Details
Main Authors: Marko Gosak, Andraž Stožer, Rene Markovič, Jurij Dolenšek, Matjaž Perc, Marjan S. Rupnik, Marko Marhl
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Physiology
Subjects:
beta cells
islets of Langerhans
self-organized criticality
intercellular dynamics
calcium waves
glucose oscillations
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.01106/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.01106/full

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