Simultaneous overexpression of GH and STAT5b genes inhibits the STAT5 signalling pathway in tilapia (Oreochromis niloticus) embryos

Simultaneous overexpression of GH and STAT5b genes inhibits the STAT5 signalling pathway in tilapia (Oreochromis niloticus) embryos

In this study, we describe the use of a STAT5 responsive element (LHRE) reporter gene to monitor the activity of the growth hormone (GH) transduction pathway following expression of heterologous fish GH and rat STAT5b in tilapia embryos and fish fibroblast cells. Our results indicate that both GH an...

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Bibliographic Details
Main Authors: Luis Fernando Marins, Arati Iyengar, Norman Maclean, Jose A. Levy, Frédéric Sohm
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2002-01-01
Series:Genetics and Molecular Biology
Subjects:
teleost
growth hormone
signal transduction
cytokine
trangenesis signal transducers and activators of transcription
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572002000300007

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572002000300007

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