Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation

Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation

Abstract Background Mesenchymal stromal cells (MSCs) are used in over 800 clinical trials mainly due to their immune inhibitory activity. Umbilical cord (UC), the second leading source of clinically used MSCs, is usually cut in small tissue pieces. Subsequent cultivation leads to a continuous outgro...

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Bibliographic Details
Main Authors: Anton Selich, Katharina Zimmermann, Michel Tenspolde, Oliver Dittrich-Breiholz, Constantin von Kaisenberg, Axel Schambach, Michael Rothe
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Stem Cell Research & Therapy
Subjects:
Umbilical cord
Clonal assays
DNA barcoding
Immunosuppression
Mesenchymal stromal cells
Secretome
Online Access:http://link.springer.com/article/10.1186/s13287-019-1376-9

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http://link.springer.com/article/10.1186/s13287-019-1376-9

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