Homeodomain interacting protein kinase 2 activation compromises endothelial cell response to laminar flow: protective role of p21(waf1,cip1,sdi1).

Homeodomain interacting protein kinase 2 activation compromises endothelial cell response to laminar flow: protective role of p21(waf1,cip1,sdi1).

BACKGROUND: In the cardiovascular system, laminar shear stress (SS) is one of the most important source of endothelial protecting signals. Physical and chemical agents, however, including ionising radiations and anticancer drugs, may injure endothelial cells determining an increase in oxidative stre...

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Bibliographic Details
Main Authors: Stefania Mattiussi, Chiara Lazzari, Silvia Truffa, Annalisa Antonini, Silvia Soddu, Maurizio C Capogrossi, Carlo Gaetano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2719102?pdf=render

Internet

http://europepmc.org/articles/PMC2719102?pdf=render

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