Progressive Fibrosis Is Driven by Genetic Predisposition, Allo-immunity, and Inflammation in Pediatric Liver Transplant Recipients

Progressive Fibrosis Is Driven by Genetic Predisposition, Allo-immunity, and Inflammation in Pediatric Liver Transplant Recipients

Aim: To determine predisposing factors of idiopathic allograft fibrosis among pediatric liver transplant recipients. Background: Protocol biopsies (PB) from stable liver transplant (LT) recipient children frequently exhibit idiopathic fibrosis. The relation between allograft inflammation, humoral im...

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Bibliographic Details
Main Authors: S. Varma, J. Ambroise, M. Komuta, D. Latinne, P. Baldin, R. Reding, F. Smets, X. Stephenne, E.M. Sokal
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:EBioMedicine
Subjects:
Pediatric liver transplantation
Donor-specific antibodies
HLA antibodies
Humoral immunity
Fibrosis
Portal inflammation
HLA-DRB1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302420

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http://www.sciencedirect.com/science/article/pii/S2352396416302420

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