Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development
<p>Abstract</p> <p>Background</p> <p>Smad4 mutant embryos arrest shortly after implantation and display a characteristic shortened proximodistal axis, a significantly reduced epiblast, as well as a thickened visceral endoderm layer. Conditional rescue experiments demons...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
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Series: | BMC Developmental Biology |
Online Access: | http://www.biomedcentral.com/1471-213X/9/54 |