CD44, hyaluronan, the hematopoietic stem cell and leukemia-initiating cells

CD44 is an adhesion molecule that varies in size due to glycosylation and insertion of so-called variant exon products. The CD44 standard isoform (CD44s) is highly expressed in many cells and most abundantly in cells of the hematopoietic system, whereas expression of CD44 variant isoforms (CD44v) is...

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Bibliographic Details
Main Author: Margot eZoeller
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00235/full