The Important Molecular Markers on Chromosome 17 and Their Clinical Impact in Breast Cancer

Abnormalities of chromosome 17 are important molecular genetic events in human breast cancers. Several famous oncogenes (HER2, TOP2A and TAU), tumor suppressor genes (p53, BRCA1 and HIC-1) or DNA double-strand break repair gene (RDM1) are located on chromosome 17. We searched the literature on HER2,...

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Bibliographic Details
Main Authors: Yingyan Yu, Wei Zhang
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/12/9/5672/