Inhibition of nasal mucosal eosinophils after immunotherapy is associated with a decrease in interleukin-13 mRNA and vascular cell adhesion molecule-1 expression

Background: Grass pollen immunotherapy is highly effective in reducing seasonal hay fever symptoms and medication requirements. Clinical improvement is accompanied by a reduction in nasal mucosal eosinophils, although the mechanism is unknown. Methods: Nasal biopsies were taken from 37 adults before...

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Bibliographic Details
Main Authors: Hiroshi Watanabe, Kayhan T Nouri-Aria, Duncan R Wilson, Samantha M Walker, Mikila R Jacobson, Stephen R Durham
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015311254