Potential Prognostic Role of <i>SPARC </i>Methylation in Non-Small-Cell Lung Cancer

Potential Prognostic Role of <i>SPARC </i>Methylation in Non-Small-Cell Lung Cancer

The silencing of <i>SPARC</i> (secreted protein acid and rich in cysteine) gene through methylation of its promoter region represents a common event in many solid tumors and it is frequently associated with tumor progression and an aggressive clinical outcome. Anyhow, the data concerning...

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Bibliographic Details
Main Authors: Federico Pio Fabrizio, Angelo Sparaneo, Andrea Fontana, Tommaso Mazza, Paolo Graziano, Angela Pantalone, Paola Parente, Flavia Centra, Natalizia Orlando, Domenico Trombetta, Annamaria la Torre, Gian Maria Ferretti, Marco Taurchini, Concetta Martina Di Micco, Evaristo Maiello, Vito Michele Fazio, Antonio Rossi, Lucia Anna Muscarella
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
<i>SPARC</i>
methylation
NSCLC
early-stage
squamous cell carcinoma
Online Access:https://www.mdpi.com/2073-4409/9/6/1523

Internet

https://www.mdpi.com/2073-4409/9/6/1523

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