Epigenetic Silencing of the MLH1 Promoter in Relation to the Development of Gastric Cancer and its use as a Biomarker for Patients with Microsatellite Instability: a Systematic Analysis

Background/Aims: Human mutL homolog 1 (MLH1) promoter methylation was reported in gastric cancer (GC). This study determined the clinicopathological, prognostic, and diagnostic effects of MLH1 promoter methylation in GC. Methods: The combined odds ratio (OR) or hazard ratio (HR) and their correspond...

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Bibliographic Details
Main Authors: Guimei Hu, Lijun Qin, Xinjun Zhang, Guoliang Ye, Tao Huang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
GC
Online Access:https://www.karger.com/Article/FullText/486354