Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation

Background. The role of exendin-4 in brown adipose tissue (BAT) activation was not very clear. This study is to verify the role of BAT involved in renal benefits of exendin-4 in diabetes mellitus (DM). Methods. In vivo, C57BL/6 mice were randomly divided into nondiabetic (control) and diabetic group...

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Main Authors: Shu Fang, Yingying Cai, Fuping Lyu, Hongbin Zhang, Chunyan Wu, Yanmei Zeng, Cunxia Fan, Shaozhou Zou, Yudan Zhang, Ping Li, Ling Wang, YaomingXue, Meiping Guan
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2020/9084567