Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathway

Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathway

This study investigated the protective role of α-linolenic acid (ALA) in myocardial ischemia/reperfusion (MI/R) injury. ALA was indicated to dose-dependently protect myocardium against I/R injury, attenuate purinergic P2X7 receptor (P2X7R) activation, prevent NF-κB activation, and inhibit tumor necr...

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Bibliographic Details
Main Authors:	Shuo Wang, Chaxian Liu, Chengxin Gong, Tao Li, Jiani Zhao, Wen Xiao, Yuanyuan Liu, Shanping Peng, Chaopeng Xiong, Rumeng Wang, Lu Ding, Xingzi Liu, Shangdong Liang, Hong Xu
Format:	Article
Language:	English
Published:	Elsevier 2018-10-01
Series:	Journal of Functional Foods
Subjects:	P2X7 receptor Myocardial ischemia Reperfusion α-linolenic acid TNF-α IL-1 β
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464618304304

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