Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathway

Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathway

This study investigated the protective role of α-linolenic acid (ALA) in myocardial ischemia/reperfusion (MI/R) injury. ALA was indicated to dose-dependently protect myocardium against I/R injury, attenuate purinergic P2X7 receptor (P2X7R) activation, prevent NF-κB activation, and inhibit tumor necr...

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Bibliographic Details
Main Authors: Shuo Wang, Chaxian Liu, Chengxin Gong, Tao Li, Jiani Zhao, Wen Xiao, Yuanyuan Liu, Shanping Peng, Chaopeng Xiong, Rumeng Wang, Lu Ding, Xingzi Liu, Shangdong Liang, Hong Xu
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Functional Foods
Subjects:
P2X7 receptor
Myocardial ischemia
Reperfusion
α-linolenic acid
TNF-α
IL-1 β
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618304304

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http://www.sciencedirect.com/science/article/pii/S1756464618304304

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