Optical Genome Mapping as a Next-Generation Cytogenomic Tool for Detection of Structural and Copy Number Variations for Prenatal Genomic Analyses

Optical Genome Mapping as a Next-Generation Cytogenomic Tool for Detection of Structural and Copy Number Variations for Prenatal Genomic Analyses

Global medical associations (ACOG, ISUOG, ACMG) recommend diagnostic prenatal testing for the detection and prevention of genetic disorders. Historically, cytogenetic methods such as karyotype analysis, fluorescent in situ hybridization (FISH) and chromosomal microarray (CMA) are utilized worldwide...

Full description

Bibliographic Details
Main Authors: Nikhil Shri Sahajpal, Hayk Barseghyan, Ravindra Kolhe, Alex Hastie, Alka Chaubey
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
optical genome mapping
OGM
structural variation
copy number variation
cytogenetics
cytogenomics
Online Access:https://www.mdpi.com/2073-4425/12/3/398

Internet

https://www.mdpi.com/2073-4425/12/3/398

Similar Items