Cancer Stem-Like Cells Enriched in Panc-1 Spheres Possess Increased Migration Ability and Resistance to Gemcitabine

Cancer Stem-Like Cells Enriched in Panc-1 Spheres Possess Increased Migration Ability and Resistance to Gemcitabine

Pancreatic cancer is one of the most lethal malignancies with poor prognosis. Previously, we found that a subpopulation of cancer stem cells (CSCs) in the Panc-1 pancreatic cancer cell line could propagate to form spheres. Here we characterized the malignant phenotypes of the pancreatic cancer stem...

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Bibliographic Details
Main Authors: Gang Zhao, Chunyou Wang, Zhiyong Yang, Tao Yin, Shanmiao Gou, Pengfei Shi, Hongji Wei
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:International Journal of Molecular Sciences
Subjects:
pancreatic cancer
Bmi-1
chemoresistance
invasion
tumorigenesis
Online Access:http://www.mdpi.com/1422-0067/12/3/1595/

Internet

http://www.mdpi.com/1422-0067/12/3/1595/

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