Acute Promyelocytic Leukemia: A History over 60 Years—From the Most Malignant to the most Curable Form of Acute Leukemia
Abstract Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) that is cytogenetically characterized by a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion of the promyelocytic leukemia (PML) and retinoic acid receptor alp...
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Format: | Article |
Language: | English |
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Adis, Springer Healthcare
2019-02-01
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Series: | Oncology and Therapy |
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Online Access: | http://link.springer.com/article/10.1007/s40487-018-0091-5 |