Acute Promyelocytic Leukemia: A History over 60 Years—From the Most Malignant to the most Curable Form of Acute Leukemia

Abstract Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) that is cytogenetically characterized by a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion of the promyelocytic leukemia (PML) and retinoic acid receptor alp...

Full description

Bibliographic Details
Main Author: Xavier Thomas
Format: Article
Language:English
Published: Adis, Springer Healthcare 2019-02-01
Series:Oncology and Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1007/s40487-018-0091-5