Hydrogel-Mediated DOX⋅HCl/PTX Delivery System for Breast Cancer Therapy

Hydrogel-Mediated DOX⋅HCl/PTX Delivery System for Breast Cancer Therapy

We used a hydrogel-mediated dual drug delivery approach, based on an injectable glycol chitosan (GC) hydrogel, doxorubicin hydrochloride (DOX⋅HCl), and a complex of beta-cyclodextrin (β-CD) and paclitaxel (PTX) (GDCP) for breast cancer therapy in vitro and in vivo. The hydrogel was swollen over 3 da...

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Bibliographic Details
Main Authors: Hoon Hyun, Young Bum Yoo, So Yeon Kim, Hyun Sun Ko, Heung Jae Chun, Dae Hyeok Yang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
injectable glycol chitosan
doxorubicin hydrochloride
beta-cyclodextrin
paclitaxel
breast cancer therapy
Online Access:https://www.mdpi.com/1422-0067/20/19/4671

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https://www.mdpi.com/1422-0067/20/19/4671

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