Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting

Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting

Activity-dependent neuroprotective protein (ADNP) mutations are linked with cognitive dysfunctions characterizing the autistic-like ADNP syndrome patients, who also suffer from delayed motor maturation. We thus hypothesized that ADNP is deregulated in versatile myopathies and that local ADNP muscle...

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Bibliographic Details
Main Authors: Oxana Kapitansky, Gidon Karmon, Shlomo Sragovich, Adva Hadar, Meishar Shahoha, Iman Jaljuli, Lior Bikovski, Eliezer Giladi, Robert Palovics, Tal Iram, Illana Gozes
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
muscular dystrophy
neuromuscular diseases
ADNP
NAP
CRISPR/Cas9
Online Access:https://www.mdpi.com/2073-4409/9/10/2320

Internet

https://www.mdpi.com/2073-4409/9/10/2320

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