M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response

M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response

Guillain–Barré syndrome (GBS), an immune-mediated disorder affecting the peripheral nervous system, is the most common and severe acute paralytic neuropathy. GBS remains to be potentially life-threatening and disabling despite the increasing availability of current standard therapeutic regimens. The...

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Bibliographic Details
Main Authors: Tong Du, Chun-Lin Yang, Meng-Ru Ge, Ying Liu, Peng Zhang, Heng Li, Xiao-Li Li, Tao Li, Yu-Dong Liu, Ying-Chun Dou, Bing Yang, Rui-Sheng Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
macrophages
exosomes
T helper 1 (Th1) cells
IFN-γ
experimental autoimmune neuritis (EAN)
Guillain–Barré syndrome (GBS)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01603/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01603/full

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