Action of tyrosinase on alpha and beta-arbutin: A kinetic study.

The known derivatives from hydroquinone, α and β-arbutin, are used as depigmenting agents. In this work, we demonstrate that the oxy form of tyrosinase (oxytyrosinase) hydroxylates α and β-arbutin in ortho position of the phenolic hydroxyl group, giving rise to a complex formed by met-tyrosinase wit...

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Bibliographic Details
Main Authors: Antonio Garcia-Jimenez, Jose Antonio Teruel-Puche, Jose Berna, José Neptuno Rodriguez-Lopez, Jose Tudela, Francisco Garcia-Canovas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5426667?pdf=render