HIV-1 subtype C transmitted founders modulate dendritic cell inflammatory responses

HIV-1 subtype C transmitted founders modulate dendritic cell inflammatory responses

Abstract Background Heterosexual transmission remains the main route of HIV-1 transmission and female genital tract (FGT) inflammation increases the risk of infection. However, the mechanism(s) by which inflammation facilitates infection is not fully understood. In rhesus macaques challenged with si...

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Bibliographic Details
Main Authors: Evelyn Ngwa Lumngwena, Simon Metenou, Lindi Masson, Claudia Cicala, James Arthos, Zenda Woodman
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Retrovirology
Subjects:
HIV-subtype C Env
Transmitter/Founder Envelopes
Inflammatory responses
Virus survival
Immunosuppression
Transmission
Online Access:http://link.springer.com/article/10.1186/s12977-020-00526-0

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http://link.springer.com/article/10.1186/s12977-020-00526-0

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