The transcriptional cofactor MCAF1/ATF7IP is involved in histone gene expression and cellular senescence.

Cellular senescence is post-mitotic or oncogene-induced events combined with nuclear remodeling. MCAF1 (also known as hAM or ATF7IP), a transcriptional cofactor that is overexpressed in various cancers, functions in gene activation or repression, depending on interacting partners. In this study, we...

Full description

Bibliographic Details
Main Authors: Nobuhiro Sasai, Noriko Saitoh, Hisato Saitoh, Mitsuyoshi Nakao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728336?pdf=render