Inside Perspective of the Synthetic and Computational Toolbox of JAK Inhibitors: Recent Updates

Inside Perspective of the Synthetic and Computational Toolbox of JAK Inhibitors: Recent Updates

The mechanisms of inflammation and cancer are intertwined by complex networks of signaling pathways. Dysregulations in the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway underlie several pathogenic conditions related to chronic inflammatory states, autoimmune diseas...

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Bibliographic Details
Main Authors: Adriana Coricello, Francesco Mesiti, Antonio Lupia, Annalisa Maruca, Stefano Alcaro
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
Janus kinase (JAK)
multitarget
inflammation
cancer
synthetic strategies
tofacitinib
Online Access:https://www.mdpi.com/1420-3049/25/15/3321

Internet

https://www.mdpi.com/1420-3049/25/15/3321

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