A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology.

It is nearly half a century past the age of the introduction of the Central Dogma (CD) of molecular biology. This biological axiom has been developed and currently appears to be all the more complex. In this study, we modified CD by adding further species to the CD information flow and mathematicall...

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Bibliographic Details
Main Authors: Mohieddin Jafari, Naser Ansari-Pour, Sadegh Azimzadeh, Mehdi Mirzaie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739447?pdf=render