Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model

Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model

Zebrafish (<i>Danio rerio</i>) larvae have gained attention as a valid model to study in vivo drug metabolism and to predict human metabolism. The microinjection of compounds, oligonucleotides, or pathogens into zebrafish embryos at an early developmental stage is a well-established tech...

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Bibliographic Details
Main Authors: Yu Mi Park, Markus R. Meyer, Rolf Müller, Jennifer Herrmann
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
zebrafish larvae model
metabolism
administration route
microinjection
HepaRG cells
mass spectrometry imaging (MSI)
Online Access:https://www.mdpi.com/1420-3049/25/19/4474

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https://www.mdpi.com/1420-3049/25/19/4474

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