Vesicular release of glutamate utilizes the proton gradient between the vesicle and synaptic cleft

Glutamate is released from synaptic vesicles following formation of a fusion pore, connecting the vesicle interior with the synaptic cleft. Release is proposed to result from either full fusion of the vesicle with the terminal membrane or by ‘kiss-and-run’, where release occurs...

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Bibliographic Details
Main Authors: Jon T Brown, Kate L Weatherall, Laura R Corria, Thomas E Chater, John Isaac, Neil V Marrion
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00015/full